Audit and Inspection Support for the National Institute of Environmental Health Sciences (NIEHS)
For more than 35 years, CSS has provided quality control assessment support to the National Toxicology Program (NTP) on studies relating to the toxicological effects of chemicals in the environment.
Audit and Inspection Support for the National Institute of Environmental Health Sciences (NIEHS).
For more than 35 years – CSS’s longest running contract – we have provided quality assessment support to the National Toxicology Program (NTP) for studies carried out on their behalf by contract laboratories regarding toxicological effects of chemicals in the environment.
CSS toxicologists verify that the required and appropriate experimental procedures were followed in every detail, that observations and results were accurately and completely recorded, that the archival data and specimens were properly organized, catalogued, and maintained to facilitate access, and that the conduct of each study was described accurately, and the data presented correctly in NTP Technical Reports. Our audit reports verify whether the information contained in the NTP Technical Report is supported by the original study records submitted to the NTP Archives.
Among the types of studies audited are pre-chronic toxicity, chronic toxicity/carcinogenicity, Reproductive Assessment by Continuous Breeding (RACB), Modified One Generation (MOG), developmental toxicity (including teratological endpoints), behavioral and neurotoxicity, immunotoxicity, and toxicokinetic. Our audit tasks have recently been expanded to include draft manuscripts of research studies being prepared for publication.
Example studies include:
Bisphenol A (BPA) used to manufacture polycarbonate plastics. This type of plastic was used to make some types of beverage containers, compact disks, plastic dinnerware, impact-resistant safety equipment, automobile parts, and toys;
Radiofrequency radiation emitted by cell phones;
Polyfluoroalkyl substances (PFAS) used in an extensive number of consumer products (Teflon). These ‘forever chemicals’ are extremely resistant to degradation in the environment;
Glyphosate, the most heavily used herbicide world-wide (the active ingredient in Roundup).
Additional Projects
Analytical Laboratory Support for Mass Transit Decontamination Research
CSS helped advance EPA’s body of knowledge for restoring subway systems after a biological incident.
Evaluation of Pesticide Safety
CSS supports the EPA Office of Pesticide Programs in evaluating the safety and potential health and environmental risks resulting from the use of pesticides and ensures that the data utilized for EPA’s regulatory decisions are scientifically sound.
Guiding Wildfire Response and Recovery
CSS supports communities following catastrophic wildfires to ensure that items discarded during site cleanup are properly identified, sorted, and sent to an appropriate disposal facility.
Service Areas
Safety, Health, & Environmental
We provide our clients with tools to protect their workforce, the public, and the environment.
Earth & Space Science Support & Operations
We deliver scientific support to advance our clients’ research goals.
Facilities Operations & Maintenance
We understand your facility support needs and deliver customized solutions.
Satellite Data Applications
Helping create a more environmentally sustainable, weather-ready, and secure nation through application of earth observation data
Environmental Resource Assessment & Management
We apply science to address challenges affecting the nation’s natural resources.
Human Health Risk Assessment
We help advance the understanding of chemical effects on people and the environment.
Get in touch
Contact us to learn more about our projects, capabilities, solutions, and service offerings.